Life cycle of malaria Outline Example | Topics and Well Written Essays - 250 words

Life cycle of malaria - Outline Example These sporozoite stage plasmodiums enter into the blood circulation (Hall and Fauci, 1640). The merozoites invade and enter vulnerable erythrocytes from where they go through differentiation and replicate over several days. They are produced in large numbers and soon rupture the erythrocytes. These results in their release back into the circulation to begin the blood stage again (Hall and Fauci, 1640). The parasites may differentiate into gametocytes while in the blood stage. On been taken up by a feeding mosquito, the gametocytes replicate and mature into male and female gametes which fuse forming zygotes that go through differentiation and replication in the mosquito gut to form sporozoites that move to the salivary glands of the mosquito from where they can be transmitted (Hall and Fauci, (1640). a. Modifications of the plasmodium cells, the infected erythrocytes, and changes in transcript abudance during maturation of the parasite within the erythrocytes as Bozdech, Llinas, Pulliam et al., (n.p.) found out. Bozdech, Zbynek, Manuel Llinas, Brian Pulliam, et. al. â€Å"The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum.† Plos Biology 1.1, (2003); n. pag. Web. 24 March 2014. Delves, Michael, David Plouffe, Christian Scheurer, Stephan Meister, Sergio Wittlin, Elizabeth A. Weinzler, Robert E. Sinden and Didier Leroy. â€Å"The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites.† PloS Med 9.2 (2012): n. pag. Web. 9 March 2014. Hall, Fenton and Anthony Fauci. â€Å"Malaria Control, Elimination, and Eradication: The Role of the Evolving Biomedical Research Agenda.† The Journal of Infectious Diseases 200.11 (2009): 1639 – 1643. Web. 9 March 2014. Pongtavornpinyo, Wirichada, Ian M. Hastings, Arjen Dondorp, Lisa J. White, Richard J. Maude, Sompob Saralamba, Nicholas P. Day Nicholas J. white and Maciej F.